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Elucidating MDLC’s molecular features
The study’s results indicate that spatial sequencing of mixed-type breast cancers could inform personalised treatment.
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Michigan University
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Atlas of the human ovary offers huge potential for new treatments
Single-cell RNA sequencing of ovaries resulted in the identification of four major cell types and four immune cell subtypes.
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Advancing the development of CTLA-4 inhibitors
A new study could result in CTLA-4 inhibitors that promote antitumour responses without causing intestinal diseases, such as colitis.
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New drug shows promise for fighting both COVID-19 and cancer
US researchers showed that the protein: GRP78, implicated in COVID-19 and cancers, is effected by the new drug HA15.
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Study finds protein H84T-BanLec is effective against all known coronaviruses and influenzas
H84T-BanLec has viral-blocking abilities by binding to polysaccharides that are present on the surface of the viruses.
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New photonic effect could accelerate drug screening processes
Researchers have shown that twisted nanoscale semiconductors can be utilised to accelerate the discovery of drugs through high-throughput screening.
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AI method reveals 17 existing drugs that may fight against COVID-19
Scientists used artificial intelligence to identify 17 existing drugs that could kill SARS-CoV-2 in cells, including a dietary supplement.
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New technique developed for identifying therapeutic nanobodies
Researchers have used a new method for discovering nanobodies to identify potential therapeutics against SARS-CoV-2 infection.
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Algorithm created to analyse large single-cell sequencing datasets
An algorithm which continuously processes new data has been developed to allow researchers to access and analyse single-cell sequencing information.
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Inhibiting IRE1α pathway could be novel therapeutic strategy for lupus
A study has revealed that blocking a molecule called IRE1α could prevent the release of neutrophil extracellular traps in lupus pathogenesis.
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Bioactive compound in ginger could be used in treatment of lupus
According to new research, the bioactive compound of ginger root, 6-gingerol, prevented disease progression of lupus in mice.
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Rod-shaped microparticles could improve immune system response to COVID-19
Researchers have suggested that neutrophils, which contribute to the development of ARDS in COVID-19 patients, could be diverted from the lungs by rod-shaped particles in a new form of treatment.
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Investigational drug kills pancreatic cells in mice by cutting off cysteine supply
Researchers have demonstrated that cysteinase, a new drug compound, can starve pancreatic cells of cysteine supply, causing ferroptosis.
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Artificial enzyme catalytic capabilities improved, say researchers
A study has shown that using a particular three-stranded structure can extend the catalytic performance of artificial metalloenzymes.
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Faster drug discovery could hit ‘undruggable’ targets
A new technique has been developed which has the potential to harness bacteria to produce billions of different drug candidates to treat diseases like cancer.
